Title: Human cancers and mammalian retroviruses: should we worry about bovine leukaemia virus? Authors
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منابع مشابه
Bovine Leukaemia Virus onco-protein Tax antigen identification in human lymphomas tissue
Background: Bovine leukaemia virus (BLV) is the primary cause of enzootic bovine leukaemia which belongs to the HTLV/BLV group of oncogenic retroviruses including Human T-cell leukaemia virus types 1, 2, and 3 and simian T-lymphotropic virus. Due to daily consumption of milk, meat and other dairy by-products, a possible role in appearing human cancers can be assumed for BLV. Materials and Metho...
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The objective of this study was to compare different antigen preparations to produce monoclonalantibodies against bovine leukaemia virus gp51SU. The four antigen preparations for immunization ofBALB/c mice were: CL: BLV-FLK cell lysate, UF: a fraction of CL (between 30 and 100 kDa), WVP: wholevirus particles and SP: with ion exchange chromatography, gp51SU was semipurified. A total of ninesucce...
متن کاملHuman T-cell Lymphotropic Virus
Retroviruses can be classified according to the morphology of their virion core or according to sequence homologies that become evident after phylogenetic analyses. Human T-lymphotropic virus type 1 (HTLV-1) is a member of the deltatype retrovirus group, other members of which include HTLV types 2, 3 and 4, bovine leukaemia virus (BLV), and simian T-cell leukaemia virus (STLV) types 1, 2 and 3 ...
متن کاملبررسی همراهی ژنوم HTLV-1 با سرطانهای مهبل و گردن رحم
Background and Aim:Today, several viruses that are responsible for the development of approximately 15% of all human tumors have been characterized.Human T cell leukemia/lymphoma virus type1 (HTLV-1) , one of the human retroviruses which causes Adult T cell leukemia and Tropical spastic myelopathy, is also associated with other diseases and cancers in humans. This virus is endemic in Khoras...
متن کاملDetection and Identification of Enzootic Bovine Leukosis (EBL) in Calves in Iran
Enzootic bovine leukosis (EBL) is known as bovine lymphosarcoma and normally affects the old cattle. EBL is caused by bovine leukemia virus (BLV), which is generally spread all around the world. This virus is transmitted via bovine blood products within and between cattle herds. Glycoprotein GP51 in the blood is responsible for cattle immune responses to BLV. This virus has been previously dete...
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